-Esophagitis due to gastro eosophageal regurgitation
-Prevention of gastric acid ingestion during and after general anesthesia in combination with the usual recommended treatment .
-Zollinger –ellison syndrome
-Healing from Helicobacter Pilori in duodenal and gastric ulcer
-Prevention relapse in patients with duodenal and gastric ulcer and severe esophagitis that were poorly responsive to customary medical treatment